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Journal of Clinical Pathways

From the Journal

Original Research
04/15/2025
Akila Visvanathan, PhD; Sarah Morton, PhD; Allan Macraild, MSc; Polly Black, MSc; Sophie Gilbert, MSc; Mark Barber, MD; Martin Dennis, MD; Richard O'Brien, MD; Gillian Mead, MD
This study explored the use of a digital platform to support shared decision-making in a stroke unit, revealing critical barriers that must be addressed to improve patient-centered outcomes.
This study explored the use of a digital platform to support shared decision-making in a stroke unit, revealing critical barriers that must be addressed to improve patient-centered outcomes.
This study explored the use of a...
04/15/2025
Journal of Clinical Pathways
From the Field
04/15/2025
Sang Chau, PharmD, BCOP; Amy VanGalder, PharmD, BCOP; Garrick Wong, PharmD; Terra Wonsettler, PharmD, MBA; Emma Domico, MS; Andrew Hertler, MD, FACP
This study discusses how Evolent is tackling the rising costs of cancer treatment by actively reducing low-value oncology care through strategic interventions.
This study discusses how Evolent is tackling the rising costs of cancer treatment by actively reducing low-value oncology care through strategic interventions.
This study discusses how Evolent...
04/15/2025
Journal of Clinical Pathways
Original Research
04/15/2025
Ibrahim Khilfeh, PharmD; Carmine Rossi, PhD; Jill Korsiak; Lilian Diaz, MSc; Bronwyn Moore, BA; Dominic Pilon, MA; Shawn Du, PhD; Lorie Ellis, PhD
In this study, researchers evaluated the total cost of care and components of health care resource use and costs in androgen receptor path­way inhibitor (ARPI)-naïve Medicare-insured patients with metastatic castra­tion-sensitive prostate...
In this study, researchers evaluated the total cost of care and components of health care resource use and costs in androgen receptor path­way inhibitor (ARPI)-naïve Medicare-insured patients with metastatic castra­tion-sensitive prostate...
In this study, researchers...
04/15/2025
Journal of Clinical Pathways
Original Research
02/18/2025
Lisa Nuccio, MSN, FNP-C; Kirsten Drabek, BS; Neha Hippalgaonkar, MD; Aseem Tiwari, MPH, MD, MBBS; Vivian Pan, MS, PhD; Kent Hoskins, MD; Pamela Ganschow, MD; Tara Maga, PhD, MS; Lara Balay, MS Ed, MS, CGC; Karine Tawagi, MD; Natalie Reizine, MD
In this study, researchers examine the clinical implementation of an oncology-directed model of delivering guideline-concordant germline genetic testing in patients living with and receiving standard-of-care treatment for advanced prostate...
In this study, researchers examine the clinical implementation of an oncology-directed model of delivering guideline-concordant germline genetic testing in patients living with and receiving standard-of-care treatment for advanced prostate...
In this study, researchers...
02/18/2025
Journal of Clinical Pathways
Original Research
02/18/2025
Lavanya Raj, MBBS, MS; Gentri Stinson, BSN, MSN, APRN; Jeffrey W. Langsam, DO; Julie DeMacio, RN, BSN
This study analyzes the clinical outcomes associated with Cigna Healthcare’s site-of-care management strategies that redirect injected and infused specialty medications from high-cost hospital outpatient setting or out-of-network providers to...
This study analyzes the clinical outcomes associated with Cigna Healthcare’s site-of-care management strategies that redirect injected and infused specialty medications from high-cost hospital outpatient setting or out-of-network providers to...
This study analyzes the clinical...
02/18/2025
Journal of Clinical Pathways
Perspectives
12/02/2024
Maggie Dietrick, MPH; Palak Patel, MHA; Tom Valuck, MD, JD
This article explores the use of artificial intelligence (AI) in health care quality measurement and tactics to mitigate bias in AI-enhanced measurement.
This article explores the use of artificial intelligence (AI) in health care quality measurement and tactics to mitigate bias in AI-enhanced measurement.
This article explores the use of...
12/02/2024
Journal of Clinical Pathways
From the Field
12/02/2024
Daniel Simmons, PharmD, MS; Rebecca Stone, MD; James Ryan, MSc; Jigna Bhalla, PharmD; Kimmie McLaurin, MS
This study models the clinical outcomes and costs associated with utilizing an HRD biomarker-guided (BMG) approach to first-line AOC maintenance compared with a non-biomarker-guided (NBMG) approach.
This study models the clinical outcomes and costs associated with utilizing an HRD biomarker-guided (BMG) approach to first-line AOC maintenance compared with a non-biomarker-guided (NBMG) approach.
This study models the clinical...
12/02/2024
Journal of Clinical Pathways
Perspectives
10/01/2024
Christine M. Wilson, MS; Gwen Darien; Kathleen D. Gallagher, MPH; Alan J. Balch, PhD, MSc
In this third installment of a three-part series on decision support tools and shared decision-making, Christine Wilson, MA, MS, and colleagues describe how patients with­in three diverse communities who are living with cancer understand and...
In this third installment of a three-part series on decision support tools and shared decision-making, Christine Wilson, MA, MS, and colleagues describe how patients with­in three diverse communities who are living with cancer understand and...
In this third installment of a...
10/01/2024
Journal of Clinical Pathways
Perspectives
10/01/2024
Sheryl Riley, RN, OCN, CMCN; F. Randy Vogenberg, PhD, FASHP
This pilot study provides a brief literature review on users, uses, and a recent electronic survey to de­termine how users use clinical pathways along with their feedback around their value.
This pilot study provides a brief literature review on users, uses, and a recent electronic survey to de­termine how users use clinical pathways along with their feedback around their value.
This pilot study provides a...
10/01/2024
Journal of Clinical Pathways
From the Field
08/15/2024
Anna Bolha, MPAS, PA; Rebecca Maniago, PharmD, BCOP; Nina Sardesh; Taylor Dias-Foundas; James Roose, MA; Colin Harvey; Marcello Ricottone; Eric Weber; Susan Sabo-Wagner, MSN, RN, OCN, NEA-BC; Brian Patrick Mulherin, MD; Andrew Hertler, MD, FACP; James Hamrick, MD, MPH
In this report, researchers discuss a real-world study of treatment selection patterns across American Oncology Network medical oncologists, which analyzed pathway adherence rates before and after a pilot project where Evolent level 1...
In this report, researchers discuss a real-world study of treatment selection patterns across American Oncology Network medical oncologists, which analyzed pathway adherence rates before and after a pilot project where Evolent level 1...
In this report, researchers...
08/15/2024
Journal of Clinical Pathways

KOL Insights

Videos
04/24/2025
Lalan Wilfong, MD
For the past 10 years, Journal of Clinical Pathways has been at the forefront of advancing evidence-based, value-driven care through clinical pathways. As we celebrate our 10th anniversary, we’re highlighting the voices of key thought leaders...
For the past 10 years, Journal of Clinical Pathways has been at the forefront of advancing evidence-based, value-driven care through clinical pathways. As we celebrate our 10th anniversary, we’re highlighting the voices of key thought leaders...
For the past 10 years, Journal...
04/24/2025
Journal of Clinical Pathways
Videos
04/24/2025
Gretchen McNally, PhD, MPH, discusses how intersectional stigmas—rooted in social biases around race, gender, socioeconomic status, and other identities—negatively affect cancer care across the continuum, influencing treatment access,...
Gretchen McNally, PhD, MPH, discusses how intersectional stigmas—rooted in social biases around race, gender, socioeconomic status, and other identities—negatively affect cancer care across the continuum, influencing treatment access,...
Gretchen McNally, PhD, MPH,...
04/24/2025
Journal of Clinical Pathways
Oncology Innovations
Videos
04/23/2025
Gordon Kuntz; Lalan Wilfong, MD
In this episode of Oncology Innovations, Gordon Kuntz and Dr Lalan Wilfong discusses the evolving role of payers and value-based care intermediaries in oncology, emphasizing the importance of whole-person support, coordinated care, and...
In this episode of Oncology Innovations, Gordon Kuntz and Dr Lalan Wilfong discusses the evolving role of payers and value-based care intermediaries in oncology, emphasizing the importance of whole-person support, coordinated care, and...
In this episode of Oncology...
04/23/2025
Journal of Clinical Pathways
Steven Monda, MD
Videos
04/23/2025
Steven Monda, MD
Steven Monda, MD, shares his research on how the origin of tumor biopsies can impact biomarker performance and treatment strategies in metastatic clear cell renal cell carcinoma.
Steven Monda, MD, shares his research on how the origin of tumor biopsies can impact biomarker performance and treatment strategies in metastatic clear cell renal cell carcinoma.
Steven Monda, MD, shares his...
04/23/2025
Journal of Clinical Pathways
Hafron Headshot
Videos
04/17/2025
Jason Hafron, MD
Jason Hafron, MD, discusses how Solaris Health developed and implemented standardized, National Comprehensive Cancer Network (NCCN)-based prostate cancer pathways across its national network to ensure consistent, high-quality care, streamline...
Jason Hafron, MD, discusses how Solaris Health developed and implemented standardized, National Comprehensive Cancer Network (NCCN)-based prostate cancer pathways across its national network to ensure consistent, high-quality care, streamline...
Jason Hafron, MD, discusses how...
04/17/2025
Journal of Clinical Pathways
Figlin
Videos
04/15/2025
Robert A. Figlin, MD
In this interview, Dr Robert Figlin discusses the promising clinical activity of belzutifan combined with cabozantinib in advanced clear cell renal cell carcinoma, highlighting its potential role in future treatment pathways, practical...
In this interview, Dr Robert Figlin discusses the promising clinical activity of belzutifan combined with cabozantinib in advanced clear cell renal cell carcinoma, highlighting its potential role in future treatment pathways, practical...
In this interview, Dr Robert...
04/15/2025
Journal of Clinical Pathways
Speicher headshot
Videos
04/11/2025
Dr Stephen Speicher highlights how evolving AI regulations, clinician collaboration, and transparent, human-centered frameworks are critical to safely integrating AI into oncology care pathways and enhancing decision-making at the point of...
Dr Stephen Speicher highlights how evolving AI regulations, clinician collaboration, and transparent, human-centered frameworks are critical to safely integrating AI into oncology care pathways and enhancing decision-making at the point of...
Dr Stephen Speicher highlights...
04/11/2025
Journal of Clinical Pathways
Videos
04/10/2025
Thomas Powles, MBBS, MD
In this interview, Dr Tom Powles discusses how updated results from the EV-302 trial confirm that enfortumab vedotin plus pembrolizumab significantly improves survival and response rates compared to standard chemotherapy in first-line...
In this interview, Dr Tom Powles discusses how updated results from the EV-302 trial confirm that enfortumab vedotin plus pembrolizumab significantly improves survival and response rates compared to standard chemotherapy in first-line...
In this interview, Dr Tom Powles...
04/10/2025
Journal of Clinical Pathways
Battiglia Headshot
Videos
04/09/2025
Tracy Battaglia, MD, MPH
In this interview, Tracy Battaglia, MD, MPH, a primary care physician and 2-time cancer survivor, discusses how equity- and evidence-based patient navigation models can drive sustainable improvements in cancer care delivery and outlines key...
In this interview, Tracy Battaglia, MD, MPH, a primary care physician and 2-time cancer survivor, discusses how equity- and evidence-based patient navigation models can drive sustainable improvements in cancer care delivery and outlines key...
In this interview, Tracy...
04/09/2025
Journal of Clinical Pathways
BDHC Thumbnail
Videos
04/07/2025
John Hennessy, MBA; Michael Kolodziej, MD
In this episode of Breaking Down Health Care, John Hennessy, MBA, and Dr Michael Kolodziej, MD, explore the complex and evolving role of private equity in health care, weighing its potential to drive innovation and efficiency against concerns...
In this episode of Breaking Down Health Care, John Hennessy, MBA, and Dr Michael Kolodziej, MD, explore the complex and evolving role of private equity in health care, weighing its potential to drive innovation and efficiency against concerns...
In this episode of Breaking Down...
04/07/2025
Cancer Care Business Exchange

In the News

News
04/24/2025
Lisa Kuhns, PhD, MD
An electronic health record (EHR)-based logistic regression model demonstrated strong performance in identifying individuals at high risk for noncardia gastric cancer (NCGC), offering a potential tool to guide targeted screening in the US,...
An electronic health record (EHR)-based logistic regression model demonstrated strong performance in identifying individuals at high risk for noncardia gastric cancer (NCGC), offering a potential tool to guide targeted screening in the US,...
An electronic health record...
04/24/2025
Journal of Clinical Pathways
News
04/15/2025
Lisa Kuhns, PhD, MD
The Myelofibrosis Symptom Assessment Form Total Symptom Score version 4.0 (MFSAF TSS v4.0) reliably captures the symptom experience of patients with myelofibrosis (MF) and effectively differentiates changes over time, supporting its role as a...
The Myelofibrosis Symptom Assessment Form Total Symptom Score version 4.0 (MFSAF TSS v4.0) reliably captures the symptom experience of patients with myelofibrosis (MF) and effectively differentiates changes over time, supporting its role as a...
The Myelofibrosis Symptom...
04/15/2025
Journal of Clinical Pathways
News
04/11/2025
Hannah Musick
A nationwide study found that breast cancer screening rates are strongly influenced by social determinants and local access to mammography, with higher rates linked to education, facility proximity, and racial demographics.
A nationwide study found that breast cancer screening rates are strongly influenced by social determinants and local access to mammography, with higher rates linked to education, facility proximity, and racial demographics.
A nationwide study found that...
04/11/2025
Journal of Clinical Pathways
News
04/10/2025
Danielle Sposato
A large retrospective study published in Scientific Reports involving 979 patients from 9 cancer centers has introduced a powerful new prognostic tool for mantle cell lymphoma (MCL), a rare and aggressive form of non-Hodgkin lymphoma.
A large retrospective study published in Scientific Reports involving 979 patients from 9 cancer centers has introduced a powerful new prognostic tool for mantle cell lymphoma (MCL), a rare and aggressive form of non-Hodgkin lymphoma.
A large retrospective study...
04/10/2025
Journal of Clinical Pathways
News
04/08/2025
Juliet Gallagher
A retrospective analysis using the IQVIA PharMetrics Plus database highlights the clinical and economic burden associated with anemia in patients with myelofibrosis (MF) initiating ruxolitinib.
A retrospective analysis using the IQVIA PharMetrics Plus database highlights the clinical and economic burden associated with anemia in patients with myelofibrosis (MF) initiating ruxolitinib.
A retrospective analysis using...
04/08/2025
Journal of Clinical Pathways
News
04/07/2025
Hannah Musick
A study of older MCL patients found significant survival gains linked to increased first-line use of rituximab-bendamustine (BR) and Bruton tyrosine kinase inhibitors (BTKis), but more modest improvements after second-line therapy.
A study of older MCL patients found significant survival gains linked to increased first-line use of rituximab-bendamustine (BR) and Bruton tyrosine kinase inhibitors (BTKis), but more modest improvements after second-line therapy.
A study of older MCL patients...
04/07/2025
Journal of Clinical Pathways
News
04/07/2025
Juliet Gallagher
A recent study published in Advanced Science has introduced a deep learning model called HER2Net, which predicts HER2 status in gastric cancer (GC) using hematoxylin-eosin (H&E)–stained pathology slides.
A recent study published in Advanced Science has introduced a deep learning model called HER2Net, which predicts HER2 status in gastric cancer (GC) using hematoxylin-eosin (H&E)–stained pathology slides.
A recent study published in...
04/07/2025
Journal of Clinical Pathways
News
04/04/2025
Grace Taylor, MS, MA
Despite targeted support, patients with cancer face ongoing and emerging financial toxicity and health-related social risks, underscoring the need for more sustainable interventions.
Despite targeted support, patients with cancer face ongoing and emerging financial toxicity and health-related social risks, underscoring the need for more sustainable interventions.
Despite targeted support,...
04/04/2025
Journal of Clinical Pathways
News
03/18/2025
Lisa Kuhns, PhD, MD
Patients with mantle cell lymphoma (MCL) who receive treatment at academic cancer centers experience longer overall survival and higher participation in clinical trials compared to those treated in community-based practices, according to a...
Patients with mantle cell lymphoma (MCL) who receive treatment at academic cancer centers experience longer overall survival and higher participation in clinical trials compared to those treated in community-based practices, according to a...
Patients with mantle cell...
03/18/2025
Journal of Clinical Pathways
News
03/14/2025
Hannah Musick
Exploring the barriers and facilitators of immigrants with disabilities accessing health care in the US and Canada, this qualitative meta-synthesis reveals the structural and cultural obstacles faced by this marginalized population and calls...
Exploring the barriers and facilitators of immigrants with disabilities accessing health care in the US and Canada, this qualitative meta-synthesis reveals the structural and cultural obstacles faced by this marginalized population and calls...
Exploring the barriers and...
03/14/2025
Journal of Clinical Pathways

Quality Outlook

Quality Outlook
03/05/2025
Bridget Doherty, MPH, MS; Silas Martin, MS; Tom Valuck, MD, JD
Johnson & Johnson’s research highlights the significant impact of the FDA’s Accelerated Approval Program, estimating that earlier access to cancer therapies has provided approximately 263 000 additional life years to patients, reinforcing the...
Johnson & Johnson’s research highlights the significant impact of the FDA’s Accelerated Approval Program, estimating that earlier access to cancer therapies has provided approximately 263 000 additional life years to patients, reinforcing the...
Johnson & Johnson’s research...
03/05/2025
Journal of Clinical Pathways
CPC + CBEx: Breaking down barriers and pushing boundaries of cancer care
Blog
08/07/2024
Winston Wong, PharmD
At CPC+CBEx, we bring together stakeholders invested throughout the entire patient journey.
At CPC+CBEx, we bring together stakeholders invested throughout the entire patient journey.
At CPC+CBEx, we bring together...
08/07/2024
Journal of Clinical Pathways
Editor in chief Winston Wong, PharmD.
Editor Insights
02/13/2024
Winston Wong, PharmD
Throughout 2023, feature articles in the Journal of Clinical Pathways offered valuable insights into the most important and compelling topics in oncology and other disease areas. This blog collects the top 5 most-read articles of the year.
Throughout 2023, feature articles in the Journal of Clinical Pathways offered valuable insights into the most important and compelling topics in oncology and other disease areas. This blog collects the top 5 most-read articles of the year.
Throughout 2023, feature...
02/13/2024
Journal of Clinical Pathways
Kendall Logan, MPH.
Quality Outlook
02/12/2024
Anne DiSalvo, MPH, MBA; Kendall Logan, MPH; Erik Muther; Tom Valuck, MD, JD
This blog post is the last in a three-part series exploring the disparities related to human papilloma virus (HPV) vaccination rates in the US.
This blog post is the last in a three-part series exploring the disparities related to human papilloma virus (HPV) vaccination rates in the US.
This blog post is the last in a...
02/12/2024
Journal of Clinical Pathways
Theresa Schmidt headshot.
Quality Outlook
02/02/2024
Tom Valuck, MD, JD; Erik Muther; Theresa Schmidt, MA, PMP, CSPO; Danny Bellet, MBA; Donna Dugan, PhD, MS; David Sloan, PhD
This past fall, leaders from the Real Chemistry Market Access team attended key quality-related events to understand trends and learn from other quality and value experts.
This past fall, leaders from the Real Chemistry Market Access team attended key quality-related events to understand trends and learn from other quality and value experts.
This past fall, leaders from the...
02/02/2024
Journal of Clinical Pathways
Anne Disalvo headshot
Quality Outlook
11/10/2023
Tom Valuck, MD, JD; Anne DiSalvo, MPH, MBA; Kendall Logan, MPH; Erik Muther
This is the second part of a 3-part blog series that explores issues related to HPV vaccination rates in the US. In this blog, the racial and ethnic disparities in HPV vaccination are explored.
This is the second part of a 3-part blog series that explores issues related to HPV vaccination rates in the US. In this blog, the racial and ethnic disparities in HPV vaccination are explored.
This is the second part of a...
11/10/2023
Journal of Clinical Pathways
Anne DiSalvo.
Quality Outlook
10/03/2023
Tom Valuck, MD, JD; Anne DiSalvo, MPH, MBA; Kendall Logan, MPH; Erik Muther
This is the first of a 3-part blog series that explores issues related to HPV vaccination rates in the US. In this blog, vaccination disparities are explored among the highest and lowest performing states.
This is the first of a 3-part blog series that explores issues related to HPV vaccination rates in the US. In this blog, vaccination disparities are explored among the highest and lowest performing states.
This is the first of a 3-part...
10/03/2023
Journal of Clinical Pathways
David Blaisdell, BA, Real Chemistry.
Quality Outlook
09/22/2023
David Blaisdell, BA; Tom Valuck, MD, JD
We previously wrote about lessons from the Oncology Care Model (OCM) that the Center for Medicare and Medicaid Innovation (CMMI) could apply to the Enhancing Oncology Model (EOM). Subsequently, CMMI recently released an evaluation report for...
We previously wrote about lessons from the Oncology Care Model (OCM) that the Center for Medicare and Medicaid Innovation (CMMI) could apply to the Enhancing Oncology Model (EOM). Subsequently, CMMI recently released an evaluation report for...
We previously wrote about...
09/22/2023
Journal of Clinical Pathways
Jacqlyn Riposo
Quality Outlook
06/08/2023
Tom Valuck, MD, JD; Jacqlyn Riposo, MBA
This blog discusses the Centers for Medicare and Medicaid Services new cell and Gene Therapy Access Model proposal and recommends different ways the Center for Medicare and Medicaid Innovation can apply quality measurement to cell and gene...
This blog discusses the Centers for Medicare and Medicaid Services new cell and Gene Therapy Access Model proposal and recommends different ways the Center for Medicare and Medicaid Innovation can apply quality measurement to cell and gene...
This blog discusses the Centers...
06/08/2023
Journal of Clinical Pathways
Winston Wong
Editor Insights
02/21/2023
Winston Wong, PharmD
This blog summarizes the Journal of Clinical Pathway's top 5 articles of 2022.
This blog summarizes the Journal of Clinical Pathway's top 5 articles of 2022.
This blog summarizes the Journal...
02/21/2023
Journal of Clinical Pathways