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FDA Approval
FDA Approves Nivolumab Plus Ipilimumab for Unresectable/Metastatic Microsatellite Instability-High or Mismatch Repair Deficient Colorectal Cancer
04/08/2025
Stephanie Holland
Based on results from the CHECKMATE-8HW trial, the FDA has approved nivolumab plus ipilimumab for patients 12 years of age and older with unresectable or metastatic microsatellite instability-high or mismatch repair deficient colorectal...
Based on results from the CHECKMATE-8HW trial, the FDA has approved nivolumab plus ipilimumab for patients 12 years of age and older with unresectable or metastatic microsatellite instability-high or mismatch repair deficient colorectal...
Based on results from the...
04/08/2025
Oncology
Marwan Fakih, MD
Conference Coverage
Optimal Botensilimab and Balstilimab Dose for Refractory Microsatellite Stable Colorectal Cancer
02/11/2025
Marwan Fakih, MD
Marwan Fakih, MD, discusses study results which identified the optimal dosage of botensilimab and balstilimab for patients with refractory microsatellite stable colorectal cancer without liver metastases.
Marwan Fakih, MD, discusses study results which identified the optimal dosage of botensilimab and balstilimab for patients with refractory microsatellite stable colorectal cancer without liver metastases.
Marwan Fakih, MD, discusses...
02/11/2025
Oncology
Thierry Andre, MD, St Antoine Hospital
Videos
Nivolumab Plus Ipilimumab Combination for Microsatellite Instability-High, Mismatch Repair-Deficient Metastatic Colorectal Cancer
02/04/2025
Thierry André, MD
Thierry Andre, MD, describes results from the CheckMate 8HW trial which evaluated nivolumab plus ipilimumab compared with nivolumab monotherapy among patients with MSI-H/dMMR metastatic colorectal cancer.
Thierry Andre, MD, describes results from the CheckMate 8HW trial which evaluated nivolumab plus ipilimumab compared with nivolumab monotherapy among patients with MSI-H/dMMR metastatic colorectal cancer.
Thierry Andre, MD, describes...
02/04/2025
Oncology
Filippo Pietrantonio, MD
Conference Coverage
Amivantamab With or Without Chemotherapy for Right-Sided Metastatic Colorectal Cancer
01/28/2025
Filippo Pietrantonio
Filippo Pietrantonio, MD, discusses updated results from the phase 1b/2 OrigAMI-1 trial, which showed that amivantamab with or without chemotherapy demonstrated durable antitumor activity among patients with right-sided metastatic colorectal...
Filippo Pietrantonio, MD, discusses updated results from the phase 1b/2 OrigAMI-1 trial, which showed that amivantamab with or without chemotherapy demonstrated durable antitumor activity among patients with right-sided metastatic colorectal...
Filippo Pietrantonio, MD,...
01/28/2025
Oncology
Anna Martling, MD, Karolinska Institutet
Videos
Aspirin Reduced Risk of CRC Recurrence for Patients With PI3K Alterations
01/28/2025
Anna Martling, MD, PhD, discusses study results which found that adjuvant daily aspirin reduced the risk of colorectal cancer recurrence among patients with PI3K alterations.
Anna Martling, MD, PhD, discusses study results which found that adjuvant daily aspirin reduced the risk of colorectal cancer recurrence among patients with PI3K alterations.
Anna Martling, MD, PhD,...
01/28/2025
Oncology
Conference Coverage
Association Between ctDNA and Disease-Free Survival Among Patients With Colorectal Cancer
01/28/2025
Allison Casey
Data from the BESPOKE CRC study found ctDNA to be prognostic of DFS within the molecular residual disease and surveillance windows among patients with stage II to stage III colorectal cancer.
Data from the BESPOKE CRC study found ctDNA to be prognostic of DFS within the molecular residual disease and surveillance windows among patients with stage II to stage III colorectal cancer.
Data from the BESPOKE CRC study...
01/28/2025
Oncology
Conference Coverage
Encorafenib Plus Cetuximab and Chemotherapy for BRAF V600E-Mutant Metastatic Colorectal Cancer
01/27/2025
Allison Casey
According to results from the BREAKWATER trial, encorafenib plus cetuximab and FOLFOX showed a significant improvement in response rate that was rapid and durable among patients with BRAF V600E-mutant metastatic colorectal cancer.
According to results from the BREAKWATER trial, encorafenib plus cetuximab and FOLFOX showed a significant improvement in response rate that was rapid and durable among patients with BRAF V600E-mutant metastatic colorectal cancer.
According to results from the...
01/27/2025
Oncology
Conference Coverage
Aspirin Reduces Risk of Colorectal Cancer Among Patients With PI3K Alterations
01/27/2025
Allison Casey
According to results from the ALASCCA trial, adjuvant daily aspirin treatment significantly reduced the rate of recurrence among patients with colorectal cancer with PI3K alterations.
According to results from the ALASCCA trial, adjuvant daily aspirin treatment significantly reduced the rate of recurrence among patients with colorectal cancer with PI3K alterations.
According to results from the...
01/27/2025
Oncology
Conference Coverage
ctDNA Determines Prognosis, Celecoxib Benefit For Patients With Stage III Colon Cancer
01/27/2025
Allison Casey
According to data from the phase 3 CALGB/SWOG 80702 study, ctDNA may predict the benefit of adjuvant celecoxib to disease-free survival and overall survival for patients with stage III colon cancer.
According to data from the phase 3 CALGB/SWOG 80702 study, ctDNA may predict the benefit of adjuvant celecoxib to disease-free survival and overall survival for patients with stage III colon cancer.
According to data from the phase...
01/27/2025
Oncology
Conference Coverage
Nivolumab Plus Ipilimumab Potential New Standard of Care for Microsatellite Instability-High, Mismatch Repair-Deficient Metastatic Colorectal Cancer
01/27/2025
Allison Casey
According to results from the phase 3, CheckMate 8HW trial, nivolumab plus ipilimumab demonstrated superior PFS compared with nivolumab monotherapy for patients with microsatellite instability-high, mismatch repair-deficient metastatic...
According to results from the phase 3, CheckMate 8HW trial, nivolumab plus ipilimumab demonstrated superior PFS compared with nivolumab monotherapy for patients with microsatellite instability-high, mismatch repair-deficient metastatic...
According to results from the...
01/27/2025
Oncology

Recent News

FDA Approval
FDA Approves Penpulimab for Patients With Non-Keratinizing Nasopharyngeal Carcinoma
04/24/2025
Stephanie Holland
On April 23, 2025, the FDA has approved penpulimab plus chemotherapy for patients with metastatic non-keratinizing nasopharyngeal carcinoma.
On April 23, 2025, the FDA has approved penpulimab plus chemotherapy for patients with metastatic non-keratinizing nasopharyngeal carcinoma.
On April 23, 2025, the FDA has...
04/24/2025
Oncology
News
Lenvatinib-Based Regimens Demonstrate Efficacy, Safety Among Pre-Treated Patients With Metastatic Renal Cell Carcinoma
04/24/2025
Stephanie Holland
According to retrospective results from the LENVA-LAT study, treatment with lenvatinib-based regimens demonstrated efficacy and safety among pre-treated patients with metastatic renal cell carcinoma.
According to retrospective results from the LENVA-LAT study, treatment with lenvatinib-based regimens demonstrated efficacy and safety among pre-treated patients with metastatic renal cell carcinoma.
According to retrospective...
04/24/2025
Oncology
News
Palbociclib Plus Endocrine Therapy May Prolong Progression-Free Survival for Premenopausal Patients With HR-Positive, HER2-Negative Breast Cancer
04/23/2025
Stephanie Holland
According to extended follow-up results from the phase 2 Young-PEARL trial, palbociclib plus exemestane and ovarian function suppression prolonged progression-free survival among premenopausal patients with HR-positive, HER2-negative...
According to extended follow-up results from the phase 2 Young-PEARL trial, palbociclib plus exemestane and ovarian function suppression prolonged progression-free survival among premenopausal patients with HR-positive, HER2-negative...
According to extended follow-up...
04/23/2025
Oncology
News
Trastuzumab Rezetecan for Patients With HER2-Mutated Non-Small Cell Lung Cancer
04/22/2025
Stephanie Holland
According to results from the phase 2 HORIZON-Lung trial, trastuzumab rezetecan demonstrated promise among patients with HER2-mutated non-small cell lung cancer.
According to results from the phase 2 HORIZON-Lung trial, trastuzumab rezetecan demonstrated promise among patients with HER2-mutated non-small cell lung cancer.
According to results from the...
04/22/2025
Oncology
News
Temozolomide as Potential Second-Line Option for Patients With Small Cell Lung Cancer
04/21/2025
Stephanie Holland
According to results from a retrospective analysis of a real-world cohort, temozolomide showed potential as a second-line option for patients with small cell lung cancer.
According to results from a retrospective analysis of a real-world cohort, temozolomide showed potential as a second-line option for patients with small cell lung cancer.
According to results from a...
04/21/2025
Oncology
News
Adding Pembrolizumab to Docetaxel Does Not Improve Survival Outcomes for Metastatic Castration-Resistant Prostate Cancer
04/21/2025
Stephanie Holland
According to results from the phase 3 KEYNOTE-921 trial, the addition of pembrolizumab to docetaxel did not significantly improve survival outcomes among previously treated patients with metastatic castration-resistant prostate cancer.
According to results from the phase 3 KEYNOTE-921 trial, the addition of pembrolizumab to docetaxel did not significantly improve survival outcomes among previously treated patients with metastatic castration-resistant prostate cancer.
According to results from the...
04/21/2025
Oncology
News
Sacituzumab Govitecan Fails to Significantly Improve Survival in Advanced Urothelial Carcinoma
04/17/2025
Stephanie Holland
According to final analysis results from the phase 3 TROPICS-04 trial, sacituzumab govitecan did not significantly improve survival among previously treated patients with advanced urothelial carcinoma.
According to final analysis results from the phase 3 TROPICS-04 trial, sacituzumab govitecan did not significantly improve survival among previously treated patients with advanced urothelial carcinoma.
According to final analysis...
04/17/2025
Oncology
News
Rituximab Plus Lenalidomide Shows Durable Responses as Frontline Treatment for Patients With Follicular Lymphoma
04/16/2025
Emily Estrada
Rituximab plus lenalidomide demonstrates long-lasting responses and improved outcomes as first-line therapy for follicular lymphoma, according to a phase 2 trial.
Rituximab plus lenalidomide demonstrates long-lasting responses and improved outcomes as first-line therapy for follicular lymphoma, according to a phase 2 trial.
Rituximab plus lenalidomide...
04/16/2025
Oncology
News
Tegafur-Uracil Maintenance Did Not Improve Survival for Patients With Locally Advanced Cervical Cancer
04/15/2025
Stephanie Holland
According to results from the phase 3 GOTIC-002 trial, low-dose tegafur-uracil maintenance therapy did not improve survival among patients with locally advanced cervical cancer.
According to results from the phase 3 GOTIC-002 trial, low-dose tegafur-uracil maintenance therapy did not improve survival among patients with locally advanced cervical cancer.
According to results from the...
04/15/2025
Oncology
News
First-Line Durvalumab Plus Platinum-Etoposide for Patients With Extensive-Stage Small Cell Lung Cancer
04/14/2025
Stephanie Holland
According to final efficacy and safety results from the phase 3b LUMINANCE trial, first-line durvalumab plus platinum-etoposide demonstrated promise among patients with extensive-stage small cell lung cancer.
According to final efficacy and safety results from the phase 3b LUMINANCE trial, first-line durvalumab plus platinum-etoposide demonstrated promise among patients with extensive-stage small cell lung cancer.
According to final efficacy and...
04/14/2025
Oncology

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