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Sara Horst, MD, on Treatment Options for IBD in 2025

Sara Horst, MD
04/10/2025

Dr Sara Horst opened the AIBD regional meeting in Nashville with a comprehensive review of the many treatment options now available for inflammatory bowel disease and how to consider positioning them in a therapeutic plan.

Sara N Horst, MD, MPH, is an associate professor of medicine and assistant chief for clinical informatics in the Division of Gastroenterology, Hepatology, and Nutrition at Vanderbilt University in Nashville, Tennessee.

Latest News

News
Upadacitinib Demonstrates Long-Term Efficacy in Crohn’s Disease With Acceptable Safety Profile
04/17/2025
Jessica Garlewicz
These results support the continued development and clinical use of upadacitinib as a treatment strategy for patients with moderate-to-severe Crohn’s disease.
These results support the continued development and clinical use of upadacitinib as a treatment strategy for patients with moderate-to-severe Crohn’s disease.
These results support the...
04/17/2025
Advances in Inflammatory Bowel Disease Network
News
Wearable Sensors Show Promise for Noninvasive Monitoring of IBD Inflammatory Markers
04/03/2025
Jessica Garlewicz
The findings suggest strong correlation between sweat-based readings and conventional serum and stool biomarkers, indicating potential for real-time disease monitoring.
The findings suggest strong correlation between sweat-based readings and conventional serum and stool biomarkers, indicating potential for real-time disease monitoring.
The findings suggest strong...
04/03/2025
Advances in Inflammatory Bowel Disease Network
News
Guselkumab Demonstrates Efficacy and Safety in Phase 3 Study for Moderate to Severe Crohn’s Disease
04/03/2025
Jessica Garlewicz
Subcutaneous guselkumab showed significant clinical and endoscopic efficacy in patients with moderately to severely active Crohn’s disease.
Subcutaneous guselkumab showed significant clinical and endoscopic efficacy in patients with moderately to severely active Crohn’s disease.
Subcutaneous guselkumab showed...
04/03/2025
Advances in Inflammatory Bowel Disease Network
News
Early Response to Upadacitinib Predicts Long-Term Improvements in Crohn’s Disease
04/03/2025
Jessica Garlewicz
Patients with early response achieved higher rates of clinical remission and reductions in fatigue and impairment.
Patients with early response achieved higher rates of clinical remission and reductions in fatigue and impairment.
Patients with early response...
04/03/2025
Advances in Inflammatory Bowel Disease Network
News
MASLD Linked to Worse Clinical Outcomes in Hospitalized Crohn’s Disease Patients
04/03/2025
Jessica Garlewicz
A new study examined 792,409 hospitalizations for Crohn's disease, of which 26,229 (3.3%) involved patients with coexisting metabolic dysfunction-associated steatotic liver disease.
A new study examined 792,409 hospitalizations for Crohn's disease, of which 26,229 (3.3%) involved patients with coexisting metabolic dysfunction-associated steatotic liver disease.
A new study examined 792,409...
04/03/2025
Gastroenterology
News
VCE-Guided Treat-to-Target Strategy Reduces Flares in Crohn’s Disease Remission
04/01/2025
Jessica Garlewicz
The study highlights the utility of mucosal assessment in driving treatment optimization, even in asymptomatic patients.
The study highlights the utility of mucosal assessment in driving treatment optimization, even in asymptomatic patients.
The study highlights the utility...
04/01/2025
Advances in Inflammatory Bowel Disease Network
News
Postoperative Microbiome Profiles Predict Crohn’s Disease Recurrence
03/25/2025
Jessica Garlewicz
A multicenter prospective study has identified specific mucosa-associated microbiome changes that precede postoperative recurrence of Crohn’s disease.
A multicenter prospective study has identified specific mucosa-associated microbiome changes that precede postoperative recurrence of Crohn’s disease.
A multicenter prospective study...
03/25/2025
Advances in Inflammatory Bowel Disease Network
News
Advances in Postoperative Crohn’s Disease Management Aim to Reduce Recurrence Rates
03/25/2025
Jessica Garlewicz
Despite significant progress in medical therapies for Crohn’s disease, a substantial number of patients still require surgical intervention.
Despite significant progress in medical therapies for Crohn’s disease, a substantial number of patients still require surgical intervention.
Despite significant progress in...
03/25/2025
Advances in Inflammatory Bowel Disease Network
FDA Alert
FDA Approves Both SC and IV Guselkumab for Crohn's Disease Among Adult Patients
03/24/2025
Rebecca Mashaw
This clearance follows last year's approval for ulcerative colitis and the first approval for subcutaneous and intravenous formulations to induce remission in adult patients with moderately to severely active Crohn's disease.
This clearance follows last year's approval for ulcerative colitis and the first approval for subcutaneous and intravenous formulations to induce remission in adult patients with moderately to severely active Crohn's disease.
This clearance follows last...
03/24/2025
Advances in Inflammatory Bowel Disease Network
News
Risankizumab Shows Efficacy in Treating Pouch Complications
03/19/2025
Rebecca Mashaw
Half of a small cohort of patients with Crohn’s disease of the pouch experienced clinical remission after 12 weeks of therapy with the IL-23 inhibitor.
Half of a small cohort of patients with Crohn’s disease of the pouch experienced clinical remission after 12 weeks of therapy with the IL-23 inhibitor.
Half of a small cohort of...
03/19/2025
Advances in Inflammatory Bowel Disease Network

Latest Podcasts

IBD Drive time logo
Podcast
IBD Drive Time: Sara Horst, MD, on the Best of ECCO
04/22/2025
Raymond Cross, MD; Sara Horst, MD
Host Raymond Cross, MD, talks with Dr Sara Horst from Vanderbilt University about their picks for the most interesting and important presentations on inflammatory bowel disease at ECCO 2025.
Host Raymond Cross, MD, talks with Dr Sara Horst from Vanderbilt University about their picks for the most interesting and important presentations on inflammatory bowel disease at ECCO 2025.
Host Raymond Cross, MD, talks...
04/22/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Perioperative Optimization of Patients With IBD
04/09/2025
Raymond Cross, MD; Karen Zaghiyan, MD; Kelly Issokson, MS, RD
Host Dr Raymond Cross leads the discussion on perioperative optimization in patients with IBD with colorectal surgeon Karen Zaghiyan, MD, and dietitian Kelly Isaacson in this episode of IBD Drive Time.
Host Dr Raymond Cross leads the discussion on perioperative optimization in patients with IBD with colorectal surgeon Karen Zaghiyan, MD, and dietitian Kelly Isaacson in this episode of IBD Drive Time.
Host Dr Raymond Cross leads the...
04/09/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Freddy Caldera, DO, on Disease Prevention in IBD
03/17/2025
Millie D. Long, MD, MPH; Freddy Caldera, DO
Freddy Caldera, DO, PhD, and IBD Drive Time cohost Millie Long, MD, discuss the new AGA best practice advice on preventing diseases and monitoring for complications in patients with inflammatory bowel disease.
Freddy Caldera, DO, PhD, and IBD Drive Time cohost Millie Long, MD, discuss the new AGA best practice advice on preventing diseases and monitoring for complications in patients with inflammatory bowel disease.
Freddy Caldera, DO, PhD, and IBD...
03/17/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Detecting and Managing Anorectal Cancer
03/04/2025
Raymond Cross, MD; Millie D. Long, MD, MPH; Jessica Korman
Andrea Bafford, MD, and Jessica Korman, MD, join Drs Raymond Cross and Millie Long to review the challenges of detecting, diagnosing, and managing anorectal cancer among patients with inflammatory bowel disease.
Andrea Bafford, MD, and Jessica Korman, MD, join Drs Raymond Cross and Millie Long to review the challenges of detecting, diagnosing, and managing anorectal cancer among patients with inflammatory bowel disease.
Andrea Bafford, MD, and Jessica...
03/04/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcasts
IBD Drive Time: Jami Kinnucan, MD, on Using Cannabis in IBD
02/12/2025
Jami Kinnucan; Raymond Cross, MD; Millie D. Long, MD, MPH
Jami Kinnucan, MD, reviews the facts and fallacies about the use of cannabis for the treatment of inflammatory bowel disease, and how to discuss the issue with patients, with IBD Drive Time hosts Raymond Cross, MD, and Millie Long, MD.
Jami Kinnucan, MD, reviews the facts and fallacies about the use of cannabis for the treatment of inflammatory bowel disease, and how to discuss the issue with patients, with IBD Drive Time hosts Raymond Cross, MD, and Millie Long, MD.
Jami Kinnucan, MD, reviews the...
02/12/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Lin Chang, MD, on IBS in IBD
01/27/2025
Raymond Cross, MD; Lin Chang
Dr Lin Chang joins hosts Raymond Cross, MD, and Millie Long, MD, to discuss how patient with inflammatory bowel disease may also have underlying irritable bowel syndrome, how to diagnose the condition, and the best options for treatment.
Dr Lin Chang joins hosts Raymond Cross, MD, and Millie Long, MD, to discuss how patient with inflammatory bowel disease may also have underlying irritable bowel syndrome, how to diagnose the condition, and the best options for treatment.
Dr Lin Chang joins hosts Raymond...
01/27/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Sara Horst, MD, on the Best of ACG
01/20/2025
Raymond Cross, MD; Sara Horst, MD
Drs Ray Cross and Millie Long discuss with guest Dr Sara Horst the best presentations and abstracts on inflammatory bowel disease from the American College of Gastroenterology scientific meeting held in October.
Drs Ray Cross and Millie Long discuss with guest Dr Sara Horst the best presentations and abstracts on inflammatory bowel disease from the American College of Gastroenterology scientific meeting held in October.
Drs Ray Cross and Millie Long...
01/20/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Frank Scott, MD, on the AGA Guidelines for Ulcerative Colitis Management
12/30/2024
In this IBD Drive Time podcast, Dr Frank Scott from the University of Colorado and host Dr Raymond Cross discuss updates in the AGA guidelines for ulcerative colitis.
In this IBD Drive Time podcast, Dr Frank Scott from the University of Colorado and host Dr Raymond Cross discuss updates in the AGA guidelines for ulcerative colitis.
In this IBD Drive Time podcast,...
12/30/2024
Advances in Inflammatory Bowel Disease Network
Millie Long
Video
Millie Long, MD, on Comparative Effectiveness in Ulcerative Colitis
10/21/2024
Dr Long reviews her presentation from the AIBD regional meeting on using comparative effectiveness data to choose from among the growing number of therapies for treating ulcerative colitis.
Dr Long reviews her presentation from the AIBD regional meeting on using comparative effectiveness data to choose from among the growing number of therapies for treating ulcerative colitis.
Dr Long reviews her presentation...
10/21/2024
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Drs James Lewis and Laura Raffals on SPARC
10/21/2024
Dr Raymond Cross hosts Drs James Lewis and Laura Raffals in a discussion of SPARC, a study of adults with inflammatory bowel disease in which patients are followed prospectively to collect data about to allow prediction of disease course and...
Dr Raymond Cross hosts Drs James Lewis and Laura Raffals in a discussion of SPARC, a study of adults with inflammatory bowel disease in which patients are followed prospectively to collect data about to allow prediction of disease course and...
Dr Raymond Cross hosts Drs James...
10/21/2024
Advances in Inflammatory Bowel Disease Network

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